New adipokines
نویسندگان
چکیده
منابع مشابه
Adipokines in pancreatic diseases
Recently, because of the growing number of obese people, the correlation between adipose tissue and numerous disorders has drawn the attention of researchers. The products of adipose tissue, adipokines: leptin, adiponectin, visfatin and resistin, affect lipid metabolism, insulin secretion and inflammatory response. Therefore, it is possible that adipokines take part in the pathogenesis of acute...
متن کاملAdipokines and aging.
Dysregulation of adipose tissue-derived bioactive molecules, termed adipokines, is recognized as common ground for insulin resistance and metabolic syndrome associated with obesity. However, adipokine dysregulation is paradoxically associated with lipodystrophy and lipoatrophy with aging. In familial partial lipodystrophic syndromes and Hutchinson-Gilford progeria syndrome, both of which are ca...
متن کاملAdipokines and insulin resistance.
Obesity is associated with an array of health problems in adult and pediatric populations. Understanding the pathogenesis of obesity and its metabolic sequelae has advanced rapidly over the past decades. Adipose tissue represents an active endocrine organ that, in addition to regulating fat mass and nutrient homeostasis, releases a large number of bioactive mediators (adipokines) that signal to...
متن کاملEpigenetic Regulation of Adipokines
Adipose tissue expansion in obesity leads to changes in the expression of adipokines, adipocyte-specific hormones that can regulate whole body energy metabolism. Epigenetic regulation of gene expression is a mechanism by which cells can alter gene expression through the modifications of DNA and histones. Epigenetic mechanisms, such as DNA methylation and histone modifications, are intimately ti...
متن کاملAdipokines protecting CKD.
Increasing incidence of chronic kidney disease (CKD) which leads to end-stage renal disease (ESRD) is one of the major health issues in the modern world and requires novel strategies for treatment. Adipose tissue has been recognized to have endocrine function and secretes a variety of hormones called adipokines. Several adipokines have been implicated in the pathogenesis of CKD and may have a s...
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ژورنال
عنوان ژورنال: Annales d'Endocrinologie
سال: 2016
ISSN: 0003-4266
DOI: 10.1016/j.ando.2016.01.001